Create a new account, on your Mac, and see if InDesign opens normally in it. If it does, then there is a corruption in your normal account.
Your recommended course of action at that point is to back up all of your data, and do a clean install of the OS. Then reinstall all of your programs, and restore your data to the hard drive.
I have done everything I can do and have gotten help from 2 people on the internet thru Adobe. I have gotten two suggestions which I followed to the letter and still my InDesign CS5 freezes on opening. I have reinstalled to no avail after uninstalling and using the Cleanup Tool for CS5. Any ideas will be appreciated on how I can get this to work.