There are some known problems dealing with the installation of copy-protected software on Vista. In particular, specific copyright technologies used by select software titles may interfere with Vista's built-in copy protection and result in an error message stating that Vista may no longer be legitimate. Microsoft is currently investigating the issue, but for the time being you can try following these instructions.
When I start the software Cambridge Advanced Learner's Dictionary, i get the message :
License data is invalid! Please contact Customer support.
What does that mean? That software had worked before.