Sorry but what 'letters' are you talking about.
Letters as in correspondence between two people, or letters as in 'letters of the alphabet'?
What does 'out of sync' mean?
Where on the screen? In an application, (which one)?
What computer are you using, and when did this start happening? What changed when it started?
how does one fix letters that sometimes appear out of sync on screen? removed Enhance Pointer Precision checkbox...tkx