Maybe you don't use the right method to log in into Safe Mode. That depends on your OS. In Windows 10 you can use the recovery drive you made or the installation disk/USB you can download.
If Safe Mode doesn't work to fix it, try a refresh or reset of Windows. Details depend on what version of Windows you have.
Pleas can someone help urgently, I have my cv and other work related files that I can not access. My laptop now sticks with please wait before the windows logon screen. Control alt delete doesn't work so I can boot into safe mode, neither does F8 & shift and I just can not access anything. Hopefully someone can help me here.

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