Look at servers you access everyday on the internet. You must know that those servers run anything and every operating system you've ever heard of and your Mac, PC access them just fine.
However it's very strange to think about connecting to that drobo across multiple interfaces. What article made you think that works?
In closing. Connect the drobo to droboshare and then to the network. All is well and done.
I have two different networks for my computers. (The reason is complicated and has to do with online backup and Comcast bandwidth caps.) All of my computers are on one network, except for one Mac that has all my photos and videos. I would like to plug a Drobo in to that Mac for backup purposes and then use the DroboShare to share those files to all the other computers (on a different network) and allow other computers to back up to the Drobo. The connection to the Mac, which is the one on the different network, would be a direct Firewire/USB connection. The various computers are Windows, Mac, and Linux.
Is this possible with a Drobo?