It's good the spyware is gone but some didn't know that spyware removal tools do not repair all the damage. Yours is simple enough to find and fix. If this ware my machine I'd use HIJACKTHIS to find the items that need removing so notepad doesn't open.
After running spyware when I boot up two identical open notepads appear on the desktop with the following -
Is this a result of running my two spaywares SpywareDetector and Spybot.
Is it harmful, what does it mean, is it harmful and what do I do about it?