Remove the Sabrent and use the motherboard ports. What happens?
I have an i7 6700, gtx960 2gb, 16gb ddr4, Liquid cooling system, 2x SSD HDs, 1x 2tb HD, Bluray drive, AL-500w EXP power supply unit, and a Sabrent "USB 3.0 super speed flash media card reader" optical drive I installed mainly as the computer never came with a media card reader slot. I have had this computer for about 10 months now.
The issue I have is when I sometimes plug in a charging device (cell phone or controller to charge) to the Sabrent optical drive's 1 USB port. After plugging into this port the computer shuts off and restarts and it has never done this with a standard USB stick. The weird thing is that I did plug in a cellphone today in that same USB port and nothing happened. So this issue seems to be intermittent.. This issue has not happened when I plugged in a charging device into the computers factory USB 3.0 ports. Could this be a bad power supply or psu control motor?
Also when the computer reboots it states "Power supply surges detected during the previous power on. Asus Anti-surge was triggered to protect system from unstable power supply unit!"
Again only has occured from my knowledge when plugging into that Sabrent's usb port (sometimes).

Chowhound
Comic Vine
GameFAQs
GameSpot
Giant Bomb
TechRepublic