Can you tell more?
- what IS your d:-drive ?
- does it still work?
- what software do you install?
- where do you install the software from?
There's a lot of info to be found in http://www.google.com/search?hl=en&q=install+error+1327 but interpreting it needs more details than you provide at the moment.
I'm using XP and when trying to install software and hardware I'm getting this message: Error 1327. Invalid Drive D:\ and the computer won't load any further. Can someone explain how to get rid of this error?