First, you've not given us the exact file name, nor the location of the infected INI/shortcut... Next, YES, if the file is important, it could cause the computer to cease opening Windows correctly.. Yes, it could be a false positive but you'll want to send a copy of the file to Avast per their instructions.
But before doing so, have you tried scanning with a separate scanner to get a "second opinion"? If not, please try the ESET online scanner using the link below.
Clicking on the link below will immediately open the download dialogue window. Download the Smart Installer to your desktop and run it. It will install a small tool to allow the online scan to run.
ESET Online Scanner
Hope this helps.
Grif
I did a scan today after two days of having problems of loading WINDOWS... I know from a previous time with INI specific 'infections' that Avast deleted it, and then I was locked out completely and had to bring my DT in and have a new 'ini' installed.
Two fold question: IS this an actual infection or a false positive? (How do I find out where this specific infected file is located in my avast program results - it isn't giving me that info.
2nd part, if I move this to the virus chest as is advised by Avast, will I be locked out again, and have to bring my computer back in to have it re-installed?
Any advice and help is appreciated.

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