Check http://www.cnet.com/forums/discussions/how-to-remove-pup-option-603542/#post-f742c795-5881-433b-a29b-6d758efe5cd3 for the list of apps I scan with.
After that it gets deep as you look are output of other apps such as autoruns, hijackthis and more. Often you have to either learn what each item does or get in line at bleepingcomputer.
I use Malwarebytes, Super Anti Spyware and HitmanPro to clear all of these out. Can range from 40-300 found. I think it is doubleclick along with a few others. After I remove the adware, everything is fine until I restart my PC, I do some normal things, and I can once again a couple of hours later. All the adware is back. I have uninstalled my browser, deleted the folder, and started from scratch..that's not it. I have used every program imaginable. I think I may have a keylogger or something injecting this adware at startup or something. Very annoying and I REALLY don't want to do a clean install because I have so much data and everything organized so perfectly. I am running Windows 10 Home.

Chowhound
Comic Vine
GameFAQs
GameSpot
Giant Bomb
TechRepublic