It would help if you told us what the popups are for. Ad-Aware and Spybot don't find anything? Also please try cwshredder and see if it finds something and please give us as much more information as you can.
Also, you can not uninstall IE. You need it for Windows Updates.
You can get cwshredder here. Make sure that you only get the ''Stand-Alone'' version. ALL windows have to be closed when you run it.
Also do an online scan at one or all of these.
Housecall (using IE with Active-X)
Housecall (all browsers using java)
Running Windows Me
I'm getting Internet Explorer popups on my computer. I have downloaded Spybot, Ad-Aware, and Hijack This. I have changed to Firefox. Internet Explorer still exists on the computer but I'm afraid if I start deleting it, I will delete something the computer needs. Popups occur at any time. In fact, right in the middle of this message. After the downloads and changing to Firefox, nothing touches the popups. I read on the web somewhere that they are coming from a file in the computer and I would have to identify that file and delete it. But there's lot of files to select from and I wouldn't know the name of it anyway. What would you suggest now?