Can you tell more:
1. Filename with extension (.dll,.exe?)
2. Subfolder of program files they are in?
3. What the details tab of their (right-click) properties says.

Moreover: how much space to those programs use on your hard disk? A good cleaning using the Disk Cleanup wizard and disabling/enable system restore easily cleans deletes 5 to 10 GB. Compared with that, I suppose it's quite minor?

Kees