You can't really. In a few specific cases you can keep Windows from regenerating certain files, if you know what you're doing and are very quick about it, but the best thing to do is probably just ignore them if you don't want to use them.
I have my own system of filing, thank you very much, and the last thing I need is for windows xp to create folders for me and stick them where it feels they ought to go; in some cases duplicating files and increasing overheads. What I would like to know is how to prevent this interfering nuisance replicating itself, as deleting doesn?t seem to have any lasting effect. Any help would be greatly appreciated.