We have a whole specialised forum for that: http://forums.cnet.com/hdtv-picture-settings-forum/
But aren't settings dependent on the environment? I think the best settings in a sunny daylight room are different from the best settings in a bedroom with dim lights.
My TV has different settings for movies, sport and news if I remember well. However, I just chose some settings I liked when looking at a show and never cared any more.
I need the best picture settings for a sharp aquos 40" 1080p hdtv 120hz LED thanks !