Noted at http://reviews.cnet.com/desktops/gateway-e-4000-series/4505-3118_7-20824814.html
Did you install Intel's chipset driver package?
Try the .exe at http://downloadcenter.intel.com/SearchResult.aspx?lang=eng&ProductFamily=Chipsets&ProductLine=Chipset+Software&ProductProduct=Intel%c2%ae+Chipset+Software+Installation+Utility
Beware that the review only noted 2 usb ports. Once in awhile people spot more on the board and think these are functional.
In closing USB 2.0 support was fixed in SP2. Hope you got it.
i have a gateway e4000 and it has 6 usb ports. i used it mainly for work and when the company closed its doors i purchased it. they took the harddrive out and i replaced it, loaded XP PRO on it, went to gateway to find drivers i need and they gave me some of them but i still had to go to MPC forum to get others. my issue is i have 6 usb ports and i can't get any of them to work but one at a time. is that a driver issue or what do i need to do to run more than one port simaltaniously. i could not get a reply from gateway or MPC.i hope you can help or at least answer thank you