Port 2280 is a TCP (Transfer Control Protocol) port used by something called LNVPOLLER. I did a little research and this does NOT appear to be anything malicious, although I admit I couldn't find an exact explanation. The only thing I could turn up was an association with the eDonkey file sharing program; you're not doing file sharing, are you?
That said, I'd continue to block it, as I assume you're already doing. There's no reason why it should be open. If you want to stop getting that popup, check the box in it that allows you to suppress it.
A good basic test for any firewall is Steve Gibson's Shields UP! at https://www.grc.com/x/ne.dll?bh0bkyd2 (scroll down to the "Proceed" button and click it).
Hope this helps,
I get the following warning that Zone Alarm has blocked FROM 192-1680.1 - TCP Port 2280.
Can anybody tell me what the H this is? It comes up every time I start my computer. Is it blocking something I need? Help. Thanks
I'm using Windows XP home edition, MSn. Explorer 7