Although I had two heart attacks and eventually by-pass surgery to replace four arteries (each had blockage with one having two blockages), my heart is actually healthy. It was a problem they finally have figured out is connected to the psoriasis I've had since I was in my early 20's. Two or three really bad outbreaks but otherwise moderate or hardly noticeable.
How it was explained to me is....psoriasis causes little 'blisters' along my vascular system and eventually start leaking causing the arteries to collapse (this was mistakenly diagnosed as 'blockages' from the usual culprit..cholesterol). Large doses of niacin (had to work my way up to that amount and will be on it for the rest of my life daily now) has been found to turn those blisters into callouses that no longer leak. It has to be the flushing type that is normally given to 'normal' heart patients or those at risk because the non-flushing type has no heart benefits at all.
Psoriasis has many side effects that doctors didn't know about for a very long time. It has its own unique form of arthritis as well (you see ads for it now called psoriatic arthritis), which I also have in my lower back and neck mostly. My hands, fortunately, are free of it.
I'm monitored every six months for signs of liver issues and have come out good. There was one time when I accidentally overdosed myself and ended up in the hospital in bad shape for three days. I take a tablet type of 250mg each in handfuls three times a day....my friend was ordering it for me one time and ordered time-released capsules of the same 250 mg without realizing it. Since they were the same dosage, I was the dummy who took them figuring it was 'the same'....but the time-release started kicking in after the third dose of the day all at the same time. Neighbor came and drove me to emergency when I could barely stand and was throwing up constantly. Local hospital couldn't figure out what was wrong even though I kept telling them so they life flighted me out at my insistence to Duke Hospital where my bypass had been done. Potassium and magnesium levels were almost non-existent and I was kept in ICU in the dark with IV tubes in my neck directly into other areas of my body to dump what I needed as fast as possible. Three days later, after being in and out (mostly out) and only aware at one point that someone was talking very softly to me (almost a cooing sound and I loved her immediately. lol) while my feet and legs were being 'manipulated' (the night nurse was putting pressure socks on me).