I don't use itunes for my podcast but the others I listen too when up to date on BOL are:
NPR: Story of the day
This week in tech
Floss Weekly (Hardly ever weekly)
Geek heavy I know. I guess I need a longer commute to get more variety.
Has anyone else discovered "Justify Your Pod"? It's a riot, a real guilty pleasure.
The podcast has writers and misc celebrities defending the embarrassing or just really odd songs on their iPods. Sadly, I don't think this would work in a virtual world like Buzztown (you need to physically abduct someone's iPod and sift through it to uncover the truly mortifying stuff).
My top favorites are This American Life, Grammar Girl, and Cranky Geeks.