Have you tried an online virus scanner (run at least 2 of them)?
Panda ActiveScan
http://www.pandasoftware.com/activescan
Bitdefender
http://www.bitdefender.com/scan/Msie/index.php
McAfee FreeScan
http://us.mcafee.com/root/mfs/default.asp
Symantec Security Check
http://security.symantec.com/sscv6/
Pc-Cillin (Trend Micro Housecall)
http://housecall.antivirus.com/housecall/start_pcc.asp
PcPitstop
http://pcpitstop.com/antivirus/default.asp
RAV
http://www.ravantivirus.com/scan/
Zee
fatal error in IE has occurred at 0028:COO11E36 in VXD VMM (01)* Error was caused by Trojan-Spy.HTML.Smitfraud.c

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