Vcache errors are common on a Windows ME machine with more than 512mb ram. Tell how much ram you have before I go to the trouble of hunting up the fix for you, in case that's not what's going on here.
I get the following message when trying to install software or using some programs.
VCACHE 01+00000E4D ERROR OE:0028:COO4E459
Just formatted the hard drive so nothing is corrupt and plenty of hard drive space, thank you.