All I can ask is...
Does your machine meet the game requirements? Some never suspect that current drivers for the 3D card and the rest of the machine are required. Some will install firewalls, pop stoppers and what else and not understand what these do to some games.
When I try to load Tiger Woods 2004 golf I sometimes get the following error.
file name: VMM(01) + 0000DC99 ERROR: 0E: 0028: C000EC99