Check the "EPSON" site for XP drivers pertaining to the particular model of 1250 you have. In addition, you should be able to find troubleshooting tips somewhere there too.
I have just upgraded from Windows 98 to Windows XP and prior to upgrade I had no problems with the scanner. Now I get a message scanner cannot be detected. I have switched USB cords but get the same message.I went to the Device manager and can find my Nikon scanner under image device but no record of my Epson scanner. I have Uninstalled the program and reinstalled but still get the same message.
Can anybody provide info on this problem.

Chowhound
Comic Vine
GameFAQs
GameSpot
Giant Bomb
TechRepublic