My Epson 1660 Perfection is NOT supported by Vista either. Epson has chosen to skip my model. I was thinking of buying another scanner, but held off. About 2 weeks ago, I found VueScan software that does run my scanner with Vista at the link above. There's a free demo, but the real program costs $40.
While it's not quite as good as the Epson software, it does work with a ton of different scanners.

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