I've seen it work on Windows and while this is an unacceptable answer it is the only one I know of today.
My printer quits when it shows that it is low on ink. Problem is it won't tell which of the 4 cartridges is low or out. I check the Supply Levels and it says, "Information Not Available". Then clever me goes to "Utility" to print a test page and determine the culprit(s) but it won't let me because, yes you guessed it, I need to "Replace Cartridge". I've gone to Epson's web page and downloaded all the current drivers for my Mac desktop Snow Leopard OS 10.6.6. When I emailed HELP at Epson, the sent me links to the drivers I have already downloaded and installed. I tell them this and they still send me the same links. Nobody's really reading my email.