"Don't do that!"
-> I had to use many tips from http://www.tweakguides.com/Bioshock_1.html to play that game.
Hola, I'm using a Soundblaster Audigy SE with the latest drivers, and software. When I try to play BioShock the sound comes out all stuttered and staticy. So I experimented with it a bit and found that if I turn off EAX and Reverb (in the game) the problem is gone. Only thing is when BioSHock was in 1.0 using EAX worked fine, now that I'm in 1.1 what is the problem?

Chowhound
Comic Vine
GameFAQs
GameSpot
Giant Bomb
TechRepublic