Let's try the CODE 39 fixes first.
Easy, safe, fixes it all too often.
Take your pick from http://www.google.com/search?hl=en&q=VISTA+CODE+39
E-Machine D5239
SN XC67A 100 08385
Windows Vista AMD 64
2 1/2 years old
Computer not talking to CD, called help line, tried to download drivers over the internet not responding. Tech came over installed new hard ware CD drive. Still not talking to each other Tech says it's the software and I need to uninstall whole system and then reinstall. Any other ways of fixing it.

Chowhound
Comic Vine
GameFAQs
GameSpot
Giant Bomb
TechRepublic