Because of a problem with the loading of the busses. The more sticks means (possibly) more chips and circuit lengths that could run into you or the board inserting an extra wait cycle.
As to compatibility issues, when a client worries like that you buy strictly from the QVL list at the maker's web site or go to Crucial.com, Kingston.com and get it done.
The motherboard supports Dual Channel and has 4 DIMM slots.
I want to purchase 32 GB to begin with (for 3D applications) but it's likely I might go for 64 GB at some point.
I got told 2x16 RAM is better than 4x8 RAM if both are dual channel kits, with same frequency and latency.
My question are:
Could I just buy the 2x16, and later on just get another kit of the same type to push it to 64 GB? (I fear compatibility issues)
Or do I go 4x8, and whenever I want to go for 64 GB I would have to sell my kit and buy a 4x16 kit?