Nope. A determined hacker will get in if you let them by say installing their apps or falling for socially engineered attacks.
You may want to have it disconnected by some tech. In most laptops it's just a matter to unplug the mic.
So I have disable the mic in my PC in Windows Settings and have no webcam attached. I keep wondering if this really protects me from someone activating my mic without my knowledge and listening to me? I do have the Malwarebytes security suite and Norton running, and sometimes my NordVPN, too, if any of that affects it.