And tell if these apps were installed prior to any OS X update.
https://www.google.com/#q=os+x+repair+user+permissions is pretty common.
I am running os x Yosemite. I have 480 GB of available storage. Every application i use (except safari terminal and text edit) is not working. For example, if I open Photo Booth, nothing happens. I press cmd+opt+esc and it says not responding. then i have to force quit. This happens with every other program. In audacity i can open it and record things. but if i save the project, i get a beach ball and i have to force quit. If i try to make a video call in Skype, same thing. All of these also happen with the adobe suite. No program will work. For some reason, the programs only work in safe boot. SOMETIMES they work in normal boot, but that RARELY ever happens. Even if it did it would only be temporary. I tried verifying and repairing disk permissions. I tried making another user account, but the same thing happened. That did not work. I tried uninstalling everything program on my mac (except default programs). I even went as far as erasing and reinstalling os x all together. Not even that solved the problem. My mac had to be taken back to the store. They said nothing was wrong with it. What could be the problem. I don't think it's a hardware issue. Don't think it could be a software issue either because I reinstalled the entire os. So what could be the problem? KEEP N MIND THAT THEY ONLY WORK IN SAFE BOOT. SO it's probably not a failing hard drive. I don't to us my computer in safe boot because my Wacom tablet will not work and the computer will be slow. Please give me a solution. This mac is the only computer I have and I need it to animate. Here are links to 2 videos so you can see the problem for yourself.