I never keep anything on my computer that I can't afford to lose. I use IMAP to access my email, so it's not stored on my computer. The stuff I can't afford to lose are stored on our network servers, which are backed up nightly.
The family home computer is pretty much the same was as well. We don't really keep anything on it that can't be replaced should the computer just go belly-up.
-Terry
I decide I'm going to make a back up of mu disk. I set the date for Friday (today. Yesterday, I break the darn thing and have to reset it back to factory.
Its such a pain.
And it happens everytime I decide to do full backups. I set a date and break before that date.
One really should just build up a disk image.
I don't worry about my data so often as it gets backed up to a portable hard disk that lives in a fire proof data safe and is also copied accross the network to a server in SF.
Whatare your back up strategies guys?

Chowhound
Comic Vine
GameFAQs
GameSpot
Giant Bomb
TechRepublic