I have used Virtual Dub for quick removal of such spaces.
It's free and well documented so I will not answer how to use it.
I have a large LaserDisc collection that I would like to convert to DVD. My PC is based on an AMD Athlon 64 3400, 1GB RAM, 160GB SATA hard drive, ATI AIW 9600, and a Plextor 708 DVD burner. I know that I can connect my LaserDisc player to a vidio-in port on the AIW to capture the stream, but I was hoping to find some software that would automatically remove the "dead-space" caused by flipping the discs and/or inserting the next one in sequence. So far, I have not been able to find any software that meets this requirement. Does anyone know of a good way to accomplish this?