Maybe the mouse is worn out. Maybe it needs batteries. Maybe neither applies. We need more details including what OS you have. My dog broke my crystal ball.
I recently started having problems with my mouse, but only on the internet. I was using internet explorer 10 and when clicking on certain links I had to click, hold down the right mouse button and hit enter for the website to open.
When I tried to sign up for joining the forum, the check box saying that I had read the agreement, when I tried to click to put a check mark in the box, it didn't work. I then opened Firefox browser and was able to join the forum.
Any help would greatly be appreciated.