Windows ME isn't crashproof. You may have used just one tool to find pests and need to find more tools. Try Adaware, Spybot, Bhodemon, Cwshredder, Housecall...

http://forums.majorgeeks.com/showthread.php?t=35407

Remember that Microsoft left the DOS based Windows with oddities that will require reboots as resources run out and more... Reboot daily.

Bob