Get your antivirus program up to date and boot into Safe Mode. Note that some viruses can hide themselves from your antivirus program in normal mode, so you really need to scan in Safe Mode. To get into Safe Mode when you first power up, hit F8 about once a second until you get the menu and select Safe Mode. Then run a full system scan.
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Microsoft has suggestions and offerings at
http://windows.microsoft.com/en-US/windows7/how-do-I-remove-a-computer-virus
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MS forum moderator Keith has some suggestions along this line at
http://answers.microsoft.com/en-us/windows/forum/windows_7-performance/windows-explorer-has-stopped-working/6ab02526-5071-4dcc-895f-d90202bad8b3
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If that fixes it, fine. If not, use System Restore to go back to a date prior to the beginning of the problem. To run System Restore, click Start -> Programs -> Accessories -> System Tools -> System Restore. Click the box that says Show more restore points.
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You can check for corrupted system files. Open an administrator command prompt and run SFC if the above doesn't help. Click START, then type CMD in the search box, right-click CMD.EXE and click Run as administrator. Then from the command prompt type sfc /scannow.
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Finally if all else fails, you can check the rather cryptic system event log. To do that click Start -> Control Panel -> Administrative Tools -> Event Viewer. Once in Event Viewer click on the system log and scroll through the entries looking for those flagged "error" to see if you can find hints as to where the problem could be.
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When you get your system back in good working order, I urge you to back your system up to an external hard drive and make regular periodic updates to it.
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I hope this helps. Good luck.
I recently obtained a virus on my laptop (vista anti-spyware 2011). I removed it using the chameleon on malwarebytes but when i restarted my laptop it would not run any programs whatsoever. I managed to get google chrome to run and i made a new desktop shortcut for it and i can now run google chrome. I think it is a problem with my registry, however im not sure. I tried to reinstall firefox, but upon attempting to i could not run the program for installation it says that the application is not found.
Any help would be much appreciated, this one has me stumped..
-Thanks!

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