It doesn't do "heuristic scanning" without special add-on, so doesn't interfere.
I have Windows 7 professional with Bitdefender as my antivirus. The AV causes the restore to fail. Bitdefender told me that I must uninstall their software (I can't disable it), run the restore, then reinstall their AV. Does anyone know of an AV that does not need to be uninstalled in order to do a system restore?