I don't have any settings to offer, since settings can vary on room size, amount of ambient light, even the color of the room can affect the picture quality.
That said, C|Net also has a picture settings forum for just these questions. I wasn't able to find a post for this specific model, however, other posters may be able to help out if you create one.
Looking for the best settings on my new samsung tv. Model # un46c6900 any help would be great. Thanks