I'm sorry to hear that you're having this issue.
With the tray empty, try to press the FF>> button to see if the unit is able to reset.
I just recently downloaded and installed the latest Firmware Upgrade to my Blu-Ray player BD-P1600. It downloaded, and installed just fine. However, when it asked me to press 1 for English during the setup, it seems that none of the buttons on my remote are doing anything. I keep pressing 1 to begin the setup portion, but nothing happens.