You'll need to be more specific since most of us here have no affiliation with Cnet.
I can say, that in general, "tune up" type programs are without any real value. Most of what they do is things like clear out the browser cache (which can actually make things slower) and delete temp files (which can cause problems). So, the odds of this program having any real worth are pretty slim.
I am running Windows XP Pro with Avast as my anti-virus. Today you sent me an email advertising a Tune-Up utility. Can I run this utility with Avast?