There is no single best software to use against ad-ware. Most effective is a combination of programs.
Many here use a combination of:
Ad-aware SE - http://www.majorgeeks.com/download506.html
Spybot-Search & Destroy - http://www.safer-networking.org/index.php?page=mirrors
SpywareBlaster - http://www.javacoolsoftware.com/spywareblaster.html
SpywareGuard - http://www.javacoolsoftware.com/spywareguard.html
Can someone please tell me what is the best software to use against ad-ware viruses. I've tried everything from Spy Sweeper, Ad-ware6, Spy Doctor, and Spy Bot...so if anyone can please let me know