Power down. Unplug AC, remove battery, press and hold the power button for 60 seconds.
Release, slip in battery (hey, if the battery is old, failing, skip this step), apply AC power, wait a minute and re-try.
Be sure that you unplug ALL USB things when you do this.
Just hot my Acer Aspire E 15 yesterday I downloaded a few programs such as Google Chrome, CCleaner and League of Legends. When i turned the laptop on (which had ran out of power during night) it took me to a blue screen not the classic one but just a blank blue screen. I tried pushing enter but that only made the screen blink. I let it stand there for 2 minutes than it turned off. I started it again and it took me to the same screen. This time I pushed Esc, this took me to "InsydeH2O Setup Utility" i hit f9 for "setup defaults but it didnt help. Now I am stuck with this. Please help me.