As previously reported, some early customers of the program reported a number of problems, the most severe of which were reports that the software caused some machines to crash.
In a statement provided to CNET News.com, Apple said it has identified one of the problems and is working on a fix.
"Apple has identified a bug in the driver software for certain ATI graphics chips which can affect a small number of systems when used with Keynote," the company said. "Apple is working on an updated driver which should be available to customers shortly."
Keynote is Apple's new $99 presentation software that competes with Microsoft's PowerPoint and is designed to be able to be file compatible with the Microsoft Office component. Apple CEO Steve Jobs unveiled the program earlier this month, saying the software was originally developed to power his keynote speeches.
"This is the presentation application you need when your presentation really counts," Jobs said at the time.