The tech-heavy Nasdaq composite index fell 34.21 points to 1,638.79, while the S&P 500 went down 3.21 to 1,103.25. The Dow Jones industrial average gained 29.71 points to 9,515.42.
Lucent Technologies shares slipped in early trading on rumors it might file for bankruptcy, although the company subsequently denied the speculation. Lucent closed Wednesday's regular trading at $6.78, down $1.07 for the session.
Among other heavily traded technology stocks, Cisco Systems dropped 6 cents to $13.69; Intel retreated $2.38 to $22.63; Microsoft slid $1.44 to $51.94, and Sun Microsystems fell 22 cents to $13.86. EMC rose $1.75 to $26.95.
Investors received yet another profit warning in the business-to-business sector. After Tuesday's software landslide, Commerce One, up 39 cents to $6, said Wednesday that it expects to post a loss of 11 cents per share for the quarter.
Commerce One's relatively mild caution helped boost other stocks identified with business-to-business commerce online. Oracle gained 23 cents to $23.48. Ariba advanced 38 cents to $4.81. FreeMarkets picked up $1.09 to $7.53.
Rational Software issued a warning Tuesday evening. The company said its business will improve in the second half of its fiscal year, but that was apparently too far away for analysts, who downgraded the stock Wednesday. Investors on Wednesday drove shares up 50 cents to $14.44, despite the downgrades.
Europe's biggest software group, SAP, rose 87 cents to $25.26, and Internet media company Yahoo gained $1.06 to $12.44 after the companies said they would jointly develop a business portal.
Solectron fell 23 cents to $16.66. The contract electronics manufacturer late Tuesday said it would cut 750 jobs.
Data analysis software vendor MicroStrategy dropped 9 cents to $2.88 after warning of larger-than-anticipated first-quarter losses.
Staff and Reuters contributed to this report.