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Serve and publish files, photos, music, and videos.
Izimi can turn your PC into a server so you don't have to post files on a hosting service.
The alpha release of Kevin Rose's latest project lets you share files, links, and other info with your friends. Sure, it's a combination of several old ideas. But it works well.
Yet another way to send large video files without sending large files (or posting them on YouTube): Quickeo.