Defragment your disks and improve computer performance and stability.
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Here is basic information for how to figure out if your computer might be infected and what to do if you think it is.
Disktrix's $30 utility lets you defragment hard drives and other storage devices a little or a lot--and view the contents of individual drive clusters, among other options.
Auslogics' Duplicate File Finder is easier to use than Digital Volcano's Duplicate Cleaner, but Duplicate Cleaner identifies more types of redundant files.
Improve the performance of XP and Vista--at least a little bit--by running its built-in disk defragmenter with your choice of command switches.
You can find a better tool for just about any system task without paying a cent. Start with the firewall, which most people would consider an indispensable piece of software.
WinContig brings selective file and folder defragmentation to Vista.
Tightening up the sectors on a drive storing hundreds of gigabytes may or may not boost your PC's performance, but it could extend your drive's life expectancy.