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OS X contains a number of hidden utilities that are generally accessed via System Preferences, but which can also be launched and used independently.
Bare Bones' TextWrangler is a very useful tool for Web developers, but lacks options for quickly previewing HTML code in your Web browser.
A quick adjustment of the timeout values for key processes can greatly speed up otherwise laggy shutdowns in OS X.
If needed, you can reduce Dock clutter by hiding the icon for persistent background and helper applications.
If a program cannot be accessed because it's outside of the limits of your display, here are a couple of options you can try to restore it.
Services in OS X offer built-in and custom options to help optimize your workflow.
With the aid of a short Automator workflow, AppleScript can have you connected to your VPN with a single keystroke.
If you are experiencing problems with a menu extra and can't seem to remove it by standard means, it may have a nonstandard implementation, which will take a couple of steps to root out and uninstall.
A reported attack method can target Apple's iMessage service and flood it with messages. So far it remains highly isolated.
If you need to get a structured list of the directories in a folder, TextWrangler can do that.