You can toggle among five levels of laser sensitivity via the Mamba's DPI switching buttons tucked into the top-left corner. A series of lights on the side of the mouse changes from red to green to indicate the selected sensitivity. It isn't terribly insightful (and a battery indicator would be more useful here), but you can still understand the progression of lights in relation to the cursor speed. As with every other button on the Mamba, Razer's software lets you customize the DPI button settings, and save them into a profile.
Thanks to its onboard memory, the Mamba also allows you to carry both profiles and macros between computers or operating system installations without having to reassign them by hand. It only requires you to install the Razer drivers on the machine, which are freely downloadable. Logitech's similar G9 and G9x gaming mice also have onboard RAM, but the SideWinder X8 does not.
Razer has implemented a decent solution for switching between wired and wireless modes. The USB cable plugs into the charging base and mouse via a clunky boot-shaped connector. Similar to other mice of this type, most notably the Sidewinder X8, the Mamba will also recharge its included battery while the mouse is in wired mode. In the Mamba's case, you have to turn off the mouse first, via a switch on its underside.