We used the G330 during a few Skype sessions and were really happy with our results. Our participating party reported a clear and audible experience.
The 8-foot cable is generous enough, plus we really liked the in-line Velcro cable tie. Also in-line is a control box with volume slider and a microphone mute toggle. The cable terminates in a 1/8-inch headphone jack and a 1/8-inch microphone input. You can consolidate these two ports into one USB using the included dongle.
Logitech also claims that using the USB dongle adds some EQ enhancements. While we heard a slight improvement when listening to music, in-game audio was much less discernable. Regardless, if you have an open USB port, we recommend taking advantage of it. Even better, the headset works with both PCs and Macs and there's no setup disc or software to bother with.
In-game audio performance was good. While there's no surround-sound support on the G330, the headset does a solid job of arranging stereo sound. We were still able to detect gunfire and enemy footsteps behind us, an effect not every stereo headset is able to produce.
In terms of actual audio quality, the G330 can sound a bit flat. There doesn't seem to be a lot of defined bass even when we sampled some beat-heavy music. The quality isn't poor; it's just missing a certain oomph that we got when testing a headset such as the Razer Carcharias.
Priced at $50, the G330 Gaming Headset is one of, if not the most, comfortable headset we've ever tested. While it may not be the best-sounding device we've listened to, gamers who are prone to extended sessions may want to sacrifice audio quality for comfort. If you'd like the best of both worlds, check out the Razer Carcharias, which go for around $80.