This side-by-side comparison of Google Maps and Apple's iOS 6 Maps shows the absence of any kind of highway exit markers on the nation's interstates. On the top Google Maps view, we've circled the exit markers in red near the junction of Highway 50 and Interstate 80 in Sacramento, Calif.
Looking for medical attention? Don't use the iOS 6 Maps app. A search for hospitals in San Francisco returned this map result, labeled with the red and white cross symbol denoting medical services as the "U Csf Medical Center & Ucsf Children's Hospital" at 1855 Folsom Street. The phone number on the listing called the UCSF Women's Options Center on Sutter Street in San Francisco. The operator there knew of no medical services located at 1855 Folsom Street.
The same location at 1855 Folsom Street in Google Maps is labeled as the "UCSF Mission Center Building", and when I called the phone number listed there, I got the voicemail for the "Mission Center Building's Night Custodial Supervisor".
New York, the Big Apple, has so many landmarks you'll want to see while on vacation -- like the Flatiron Building, which has two locations apparently -- one of which is in the middle of 5th Avenue a block away from the actual location.
Looking to visit Point Reyes Lighthouse, north of San Francisco? Don't try to find it with iOS 6 Maps. A search for "Point Reyes Lighthouse" finds only the Point Reyes Lighthouse Road (which isn't the name of the road).