The IS 350 uses a 3.5-liter V-6 engine with a unique fuel delivery system. It has direct injection for higher engine speeds, and port injection for low-speed driving. The former delivers power, and the latter reduces engine noise.
When it launched the IS 350 and IS 250, Lexus only offered all-wheel drive on the IS 250, but now is extending it to the IS 350. This all-wheel-drive system defaults to 70 percent torque to the rear wheels, but can adjust to a 50/50 split as needed.