While keyboard layout seems like something that is (or should be) set in stone, Guru'board's Miniguru is trying to shake the keys up a bit.
I'm all for anyone trying to improve upon previous technologies, but typing is something that is so natural to me at this point that changing functions and placements makes me nervous. (At least on U.S. keyboards; it took me a long time to become fluent on a French one.)
But maybe the Miniguru (PDF) deserves a chance. This keyboard's goal is to keep the user's fingers on the home row as often as possible, which is supposed to make typing quicker and more efficient.
Read more of "Guru'board's Miniguru keyboard tries to make typing easier, quicker" at ZDNet's The ToyBox.